NOS3 and type 2 diabetes mellitus: 7 Makino Makino N N Maeda Maeda T T Sugano Sugano M M Satoh Satoh S S Watanabe Watanabe R R 2005 2005 High serum TNF-alpha level in Type 2 diabetic patients with microangiopathy is associated with eNOS down-regulation and apoptosis in endothelial cells.