FOS and neoplasm: To address this point, both AP-1 content and phospholipid synthesis capacity were examined in vitro in CP excised from 7-month-old tumor bearing-NPcis animals expressing high amounts of c-Fos (non-treated NPcis or treated with SO intra-cranially during 28 days as in Fig. 5A) or having low/null content of c-Fos (treated intra-cranially with ASO or C57BL/6J fos KO mice), and in untreated C57BL/6J WT animals.