CD4 and infection: In a study of 164 HIV-infected persons in Uganda (117 with incident infections), of which 65 were subtype A and 99 were subtype D, the relative hazard of AIDS-free survival was 1.39 (95% CI, 0.66-2.94, p = 0.39) for subtype D versus A. Those infected with subtype D and A/D recombinants also had a more rapid CD4 T cell decline, although this did not attain statistical significance [14].