Likewise, while characterizing ashwagandha and its molecular mechanisms Wadhwa et al provided the first example that phytochemical(s) have both anti-cancer and anti senescent activities and pointed towards the molecular link between aging and cancer using normal human fibroblasts through decreased accumulation of molecular damage, down-regulation of the SA-β gal activity and the senescence marker protein, p21(WAF-1), protection against oxidative damage, and induction of proteasomal activity [45]. Here, CDKN1A is linked to cancer.