In addition to BRCA1 (93.7 ± 6.6% vs 72.8 ± 20.7%, P = 0.0044), significant differences in tumor volume were observed between positive and negative γH2AX (78.4 ± 17.4% vs 65.6 ± 26.8%, P = 0.0429) and Rad51 baseline foci groups (78.1 ± 18.9% vs 63.6 ± 24.4%, P = 0.0351) [Additional file 2b]. The gene discussed is RAD51; the disease is neoplasm.