PARP1 and Salmonella Infections: However, the role of PARP in the pathogenesis of Salmonella enteritis and the effect of the PARP-1 inhibitor PJ-34 and genetic knock down of PARP-1 siRNA on the inflammatory response of enterocytes to Salmonella infection are not known, prompting us to investigate the role of PJ-34 in Salmonella-induced intestinal inflammation and its mechanisms.