PDPN and carcinoma: There was no statistically significant correlation between podoplanin status and the severity of dysplasia: 5 (36%) of the 14 lesions with mild dysplasia, 9 (35%) of the 26 lesions with moderate dysplasia, and 23 (52%) of the 44 lesions with severe dysplasia/carcinoma "in situ" exhibited positive podoplanin expression (P = 0.28).