In addition, we performed double-label immunofluorescence in a number of Lo-MYC and Hi-MYC mice with antibodies against p63 (another basal cell marker) and MYC, and we found that in PIN lesions only cells devoid of p63 nuclear staining were strongly positive for MYC (data not shown). Here, MYC is linked to prostate intraepithelial neoplasia.