MYC and prostate intraepithelial neoplasia: While we cannot yet determine why there is a discrepancy between these findings by Kim et al. and our findings using Lo-MYC, Hi-MYC, and Super-Lo-MYC, in terms of the issue of whether all cells with MYC overexpression appear morphologically transformed into PIN cells, it is possible that there are mouse strain differences in the ability of MYC to directly transform prostate luminal cells.