FOXM1 and skin basal cell carcinoma: Given the direct induction of genomic instability by FOXM1B in NHEK, and that FOXM1B induced instability in oral mucosal keratinocytes can be augmented by nicotine [10], we were interested to know whether UVB, known to be an etiological factor in BCC formation [18], would also augment genomic instability in primary NHEK.