Interestingly, in both healthy and tumour tissues of patient A, bearing a colorectum carcinoma relapse, all observed single point transitions in TP53 transcripts, with the exception of mutations at position 628 (A>G) and 789 (T>C), have been reported in a different tumour [IARC TP53 mutation database, 13]. Here, TP53 is linked to neoplasm.