Some of these markers identified using this technique are: (1) prostasin a serum marker for ovarian cancer [11]; (2) Mesothelin (MSLN) [12,13], (3) WFDC2 (HE4) a glycoprotein [14] (4) osteopontin [15]; (5) Bikunin [16]; (6) mammaglobin-2 (MGB2) [17]; (7) discoidin domain receptor 1 (DDR1) [18]; (8) claudin 3 (CLDN3) [18]; (9) epithelial cell adhesion molecule (Ep-CAM) [18]; and (10) E-cadherin [18]. The gene discussed is CLDN3; the disease is ovarian cancer.