Similar symptoms and findings are also seen in Cushing's syndrome including ectopic ACTH syndrome and genetic diseases such as congenital adrenal hyperplasia, mineralocorticoid receptor abnormalities, Liddle syndrome, and the syndrome of apparent mineralocorticoid excess [10,11], although the possibility of these conditions could also be excluded because the patient was too old for congenital and genetic causes and had not experienced a similar disorder previously, in addition, his condition improved rapidly after the withdrawal of licorice containing 'tekumut' and replacement of K+. The gene discussed is NR3C2; the disease is Cushing syndrome due to macronodular adrenal hyperplasia.