ELANE and chronic myelogenous leukemia, BCR-ABL1 positive: PRTN3 (also known as PR3) is located ~4 kb upstream of ELA2 on human chromosome 19 and its expression has been shown to be co-regulated with ELA2. Our results confirm this co-regulation as well as indicating that, at least in our patient cohort, the transcriptional regulation of these two genes is not uncoupled in CP CML patients (Figure 3B and 3C).