To determine if the increased expression of CD7 in lin-CD34+ CML cells is associated with hypomethylation of the CD7 promoter region, we isolated DNA from lin-CD34+ cells from one normal (N1) and three CML (CML1, 4, 6 and 10) samples. This evidence concerns the gene CD34 and chronic myelogenous leukemia, BCR-ABL1 positive.