Previous studies have demonstrated important associations of clock genes with sleep and mood disorders, as for example between PER2 variants and familial ASPS [44], [72], between PER3 variants and diurnal preference and DSPS [46], [47], and between CLOCK and mood disorders [32], [33], [34] and human diurnal preference [73]. This evidence concerns the gene CLOCK and alveolar soft part sarcoma.