PPARG and neoplasm: In addition to adipose tissue, the presence of PPARγ has been demonstrated in a wide variety of tumor cells, which include osteosarcoma cell lines (MG-63, G292, SAOS, U2OS) [4,5], human breast cancer cell lines (MCF-7, MDA-MB-231) [6,7], bladder and prostate cancer cell lines (TSU-Pr1, DU145) [7,8] and a murine mammary tumor cell line (LMM3) [9].