Data obtained from COX-2 inhibitor pretreatment followed by infection (4 h, 8 h, 24 h) or cells silenced for COX-2 and then infected for different time points (4 h, 8 h, 24 h) is presented as fold reduction compared to signals obtained from untreated KSHV infected cells, and KSHV infected si-C-HMVEC-d at respective time points (Table S4). Here, PTGS2 is linked to infection.