Almost 85% of the ADPKD cases result from mutations in the PKD1 gene on chromosome 16 that encodes polycystin-1 [6], whereas mutations in the PKD2 gene on chromosome 4 encoding polycystin-2, are responsible for the remaining 15% of the cases [7], [8]. Here, PKD2 is linked to autosomal dominant polycystic kidney disease.