FOXL2 and blepharophimosis, ptosis, and epicanthus inversus syndrome: The transcription factor Foxl2 is vital to ovarian function as evidenced by the identification of mutations in the gene encoding FoxL2 that result in the condition known as blepharophimosis/ptosis/epicanthus inversus syndrome (BPES) and in some cases, premature ovarian failure (POF) [1].