The initial associations published by Mannila et al. [12-14] supporting a role of FGG-FGA and FGG-FGB haplotypes in myocardial infarction risk have not been replicated by other investigators that studied single SNPs and haplotypes in FGA, FGB and FGG genes in MI or CAD phenotypes [15-18]. This evidence concerns the gene FGB and myocardial infarction.