The IL-10-/- knock-out mice display increased CCL28 expression in the stomach and Peyer's patches indicating that IL-10 may be CCL28 suppressive.[6] Studies showing CCL28 production in nasal and bronchial epithelial cell lines have suggested that it might also play a role in allergic respiratory diseases such as bronchial asthma (BA). Here, IL10 is linked to breast angiosarcoma.