In an attempt to validate these findings, we correlated the protein expression of SOX2 with that of FGFR2 by TMA immunohistochemistry analysis and found that nuclear SOX2 protein levels correlated significantly with cytoplasmic FGFR2 levels in lung SCC histological tissue specimens (Figure S2) but not in adenocarcinomas (data not shown). Here, FGFR2 is linked to adenocarcinoma.