The expression in prostate cancer of several MMPs and TIMPs, such as MMP-2, -7, -9, -13 and -14, TIMP-1, -2 and -3, has been recently reported (Brehmer et al, 2003; Pang et al, 2004; Zhang et al, 2004; Morgia et al, 2005; Riddick et al, 2005; Semaan et al, 2005; Cardillo et al, 2006). This evidence concerns the gene TIMP1 and prostate carcinoma.