TNF and endothelial dysfunction: Some potentialgene targets that predispose the vasculature to endothelial dysfunction and a"proatherogenic" phenotype are pro-inflammatory molecules such as interleukin-6(IL-6), tumor necrosis factor-α (TNF-α) monocyte chemoattractant protein 1 (MCP-1), receptor for advanceglycation endproducts (RAGE) and the pro-oxidant enzyme NADPH oxidase [9-11].