In the case of resveratrol, this includes SIRT1 activation,inhibition of cyclooxygenase and NFκB, induction of antioxidant enzymes,and activation of AMPK in vivo [13,44], in addition to the inhibitionof the leukemia-related kinases and S6K1 reported here (Supplementary Table 1). Here, SIRT1 is linked to leukemia.