LAMB2 and neoplasm: Since the first laminin was isolated in 1979 from the mouse Engelbreth–Holm–Swarm (EHS) tumour (Timpl et al., 1979), 11 distinct laminin genes (α1–5, β1–3, γ1–3) have been identified (Miner, 2008; Miner and Yurchenco, 2004).