Indeed, in a population-based genetic study that included 7,899 participants, individuals that carried a T-87C polymorphism in the FABP4 gene, which reduces the transcriptional efficiency of the FABP4 gene, had lower serum triglyceride levels and significantly reduced risk for coronary heart disease and type 2 diabetes compared with subjects homozygous for the wild-type allele [26]. This evidence concerns the gene FABP4 and type 2 diabetes mellitus.