In tauopathies such as AD, CBD, PSP, and Pick's disease, tau is the major constituent of intracellular inclusions, and the fact that these can occur not only in neurons but also in astrocytes and oligodendrocytes points out that glial cells contribute to the pathogenesis of neurodegenerative diseases [8]. This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.