In A/J Tsc2+/- mice, cystadenoma score per kidney in untreated animals at 9 months of age is 74.4, and cystadenoma score per kidney is 41.13 in the groups treated daily × 4 weeks, but 21.50 in the group treated daily × 4 weeks then weekly × 8 weeks (Table 1). Here, TSC2 is linked to cystadenoma.