TGF-β1, TGF-β2, and TGF-β3 isoforms were detected in all tested samples obtained from normal corneas (TGF-β1 Me=4,693.0 copies/μg RNA; TGF-β2 Me=719.0 copies/μg RNA; TGF-β3 Me=3,844.7 copies/μg RNA) and bullous keratopathy corneas (TGF-β1 Me=5,553.0 copies/μg RNA; TGF-β2 Me=738.9 copies/μg RNA; TGF-β3 Me=2,176.5 copies/μg RNA). This evidence concerns the gene TGFB2 and vesiculobullous skin disease.