PGGT1B and melanoma: In the current study we used the LB1319-MEL human melanoma model to investigate the effects of 4 days of in vitro treatment with hIFN-γ (50 IU/mL) and/or GGTI-298 (10 μM) on the expression of TAP1, TAP2, tapasin, PA28, LMP2, LMP7, and LMP10 proteins (Figure 4).