Unfavourable outcome at 3 months after stroke was associated with MBL-sufficient genotype (OR 10.85, 95% CI 62.94–1.87, p = 0.008) and MBL levels (OR 1.29, 95% CI 1.69–1.02, for every 500 units increase, p = 0.04) in a logistic regression model adjusted for age (OR 1.06, 95% CI 1.00–1.12, p = 0.04), sex (OR 0.32, 95% CI 0.09–1.16, versus male gender, p = 0.08), and initial stroke severity (OR 4.14, 95% CI 2.20–7.88, for each quartile of NIHSS score, p<0.0001). The gene discussed is MBL2; the disease is stroke disorder.