PSAP and posterior cortical atrophy: In addition, using other PCa progression models of isogenic cell lines, we observed consistent data for increased PSAP expression level from normal, poorly tumorigenic, or non-tumorigenic cells to androgen-independent and/or highly invasive and metastatic cell lines such as LNCaP/C4-2B, PC-3/PC-3M, and p69-M12-M2182 (see additional file 1).