A scatter-plot analysis revealed that fifty-eight percent (28/48) of breast ductal tumor tissues express KLF6 both in the nucleus and cytoplasm (Fig. 4A); additionally, ductal breast tumor tissues expressing and non-expressing nuclear KLF6 revealed a significant increase (p = 0.005; student t test) of the cytoplasmic stain (score mean 2.56 versus 1.99, respectively; see Fig. 4A and Table S3). Here, KLF6 is linked to breast neoplasm.