HNF4A and fetal growth restriction: Differences in DNA methylation at the HNF4A promoter were confirmed by MassArray, with the informative HpaII site showing hypermethylation in IUGR compared to controls (65.7% and 59.6% methylation, respectively; p<0.01), consistent with the HELP data (log2(HpaII/MspI) = 1.89±0.42 and 3.46±0.60, respectively; p = 0.00006).