GJB2 and hearing loss disorder: The three most significantly associated SNPs for hearing loss are all located at the GJB2/GJB6 locus on 13q12.1 (Figure 8), including rs870729 near GJB6 (p = 3.38×10−11, OR: 1.69), rs3751385 within GJB2 (p = 1.50×10−9, OR: 1.63), and rs7329467 within GJA3 (p = 6.87×10−8, OR: 1.68).