Dock3 has been implicated in one family with an attention deficit and hyperactivity disorder (ADHD)-like clinical syndrome [47] while Slc35d3 might function in striatonigral-specific protein glycosylation potentially implicated in the childhood hyperkinetic movement disorder Sydenham chorea of which the pathophysiology is linked to antibodies that recognize sugar moieties of glycoproteins on MSNs [48]. The gene discussed is DOCK3; the disease is attention deficit-hyperactivity disorder.