In contrast to CCND1 and D3, which are often differentially over-expressed in PDAC [5], CCND2 appears to play a role mainly in the proliferation of pancreatic islet β-cell [6], and its mRNA expression was infrequently detected in PDAC and pancreatic cancer cell lines [5,7]. The gene discussed is CCND1; the disease is pancreatic neoplasm.