AICDA and T-cell non-Hodgkin lymphoma: Factors interacting with AID might also be needed to restrict the mutator activity of AID to the immunoglobulin loci and protect genome integrity: For example, constitutively expressed AID leads to T cell lymphomas and lung micro-adenomas in transgenic mice [9], and AID expression has been linked to oncogenic translocations [10], [11] and inflammation-associated cancer [12]–[14].