ST13 is part of a number of marker genes that were recently proposed as possible biomarkers in PD [55] and MAPT is linked to neurologic disorders associated with dementia syndromes, such as Alzheimer's disease, Pick's disease, frontotemporal dementia, agryophillic grain disease, and progressive supranuclear palsy [56]. Here, ST13 is linked to early-onset autosomal dominant Alzheimer disease.