We assessed the serum levels of cytokines (IL–1, IL–2,IL–4, IL–6, IL–8, IL–10, IFN–gamma, TNF–alpha, GM–CSF), chemokines (MCP–1 and MIP–1alpha)and growth factors (VEGF and bFGF) in laryngeal cancer patients before, during and after surgery. Here, IL4 is linked to laryngeal carcinoma.