FGFR2 and craniosynostosis: Interestingly, identical FGFR2 mutations (e.g. C278F, G298P, and C342T) have been found in patients carrying the diagnosis of Crouzon, Pfeiffer, and Jackson-Weiss craniosynostosis syndromes, suggesting that these entities may represent a clinical spectrum with possible genetic modifiers [31-33].