While CSE caused a decrease of intracellular interferon gamma (IFN-γ) production and increase of IL-10 production by NK cells in all cases, the effects were not significant (IFN-γ: 10.4% vs. 5.6%, n = 5, p = 0.09, IL-10: 1.7% vs 11.5%, n = 5, p = 0.1; Figure 5C) upon tumour challenge. The gene discussed is IL10; the disease is neoplasm.