Several molecular markers like FLT3-ITD, MLL, CEBPA (CCAAT/enhancer binding protein) or BAALC (brain and acute leukemia, cytoplasmic) further characterize some of these patients but there is still highly unmet medical need for other factors to establish a clear prognostic profile in every individual patient [28,29]. This evidence concerns the gene FLT3 and acute leukemia.