Furthermore, even when Gleason score only was added to the model, PTEN did not remain a significant independent prognostic factor for PCa survival (HR=1.61, 95% CI=0.99–2.62, P=0.05) or overall survival (HR=1.16, 95% CI=0.82–1.65, P=0.41). This evidence concerns the gene PTEN and posterior cortical atrophy.