CRP and neoplasm: In a regression model of CRP (incorporating MIC-1, disease stage, tumour grade, percentage weight loss, diet score and KPS, i.e., those factors found to correlate with CRP), plasma MIC-1 concentration (P=0.003), diet score (P=0.001), and tumour grade (P=0.033) were significant determinants (r2=0.179; Table 3).