The logistic regression analysis revealed that the NOS3 mutant allele, smoking, family history, DBP, and LDL-C were independent risk factors for CAD (P=.004, P=.001, P=.006, P=.001, and P=.001, respectively), whereas DBP, cholesterol, HDL-C, and TG were not independent risk factors for CAD (Table 4). Here, NOS3 is linked to coronary artery disorder.