Analysis of 3SEQ data from both frozen tissue and FFPET revealed several related cancer-associated pathways (prostate cancer, VEGF signalling, acute myeloid leukemia) containing a number of genes known to be important in carcinogenesis (AKT2, IGF1, BAD, PIK3R1, CCND1, PML, RARA), whose concerted role in SFT has not previously been characterized. Here, PML is linked to Familial prostate cancer.