PDCD4 and neoplasm: In addition, it has been reported to counteract the expression of putative tumor-suppressive targets, such as phosphatase and tensin homolog deleted on chromosome 10 (PTEN), programmed cell death 4 (Pdcd4), tropomyosin 1, maspin and reversion-inducing cysteine-rich protein with kazal motifs [7,10-12,15-21].