INS and hyperinsulinism: Moreover, this study is, to our knowledge, the first to describe a correlation between FTO rs9939609 and insulin resistance or hyperinsulinemia in PCOS patients reflected in fasting insulin, HOMA-IR as well as in AUCI levels After strictly controlling for the multiple statistical tests performed here (multiple phenotypes and multiple SNPs) the adjusted p-value for FTO rs9939609 and fasting insulin was 0.062 and the related effect, though weaker, was still present even after statistically correcting for BMI.