Moreover, this study is, to our knowledge, the first to describe a correlation between FTO rs9939609 and insulin resistance or hyperinsulinemia in PCOS patients reflected in fasting insulin, HOMA-IR as well as in AUCI levels After strictly controlling for the multiple statistical tests performed here (multiple phenotypes and multiple SNPs) the adjusted p-value for FTO rs9939609 and fasting insulin was 0.062 and the related effect, though weaker, was still present even after statistically correcting for BMI. Here, INS is linked to Insulin resistance.