For example, D2E7 (a fully humanised anti-TNF-α monoclonal antibody), infliximab (a chimeric immunoglobulin G1 monoclonal antibody against TNF-α), pegylated recombinant humanised sTNF-R1, pegylated humanised anti-TNF-α fragment (CDP870) and TNF-α synthesis inhibitors (p38 kinase inhibitors) have now been used to treat various tumours (Szlosarek and Balkwill, 2003; Garber, 2009). The gene discussed is TNF; the disease is neoplasm.